| September
14, 2006
BioMimetic Therapeutics’
Clinical Investigators to Receive
Award from American Academy of Periodontology
for Outstanding Publication
Clinical Investigators to Present
Data at Annual AAP Meeting
Franklin, Tenn. – September
14, 2006 - BioMimetic Therapeutics,
Inc. (NASDAQ: BMTI) today announced
that Company president and CEO, Dr.
Samuel E. Lynch, along with his co-authors,
will be honored with the prestigious
American Academy of Periodontology’s
R. Earl Robinson Regeneration Award
for the scientific publication they
authored entitled Platelet-derived
Growth Factor Stimulates Bone Fill
and Rate of Attachment Level Gain:
Results of a Large Multicenter Randomized
Controlled Trial. The publication
details the positive results of the
pivotal trial for the Company’s
lead product GEM 21S®, which was
approved by the FDA in November 2005
for the treatment of periodontal disease
and gingival recession. The award
will be presented at the 92nd Annual
Meeting of the American Academy of
Periodontology (AAP) in San Diego,
CA on Saturday, September 16, 2006.
The R. Earl Robinson Regeneration
Award was established by Dr. R. Earl
Robinson to encourage research in
periodontal regeneration. It is presented
to the author(s) of the peer-reviewed
published paper that has contributed
most to the knowledge of periodontal
regeneration in a given calendar year.
Dr. Lynch’s co-authors on the
article include Myron Nevins, DDS,
William V. Giannobile, DDS, Michael
K. McGuire, DDS, Richard T. Kao, DDS,
James T. Mellonig, DDS, James E. Hinrichs,
DDS, Bradley S. McAllister, DDS, Kevin
G. Murphy, DDS, Pamela K. McClain,
DDS, Marc L. Nevins, DMD, David W.
Paquette, DMD, Thomas J. Han, DDS,
Michael S. Reddy, DMD, Phillip T.
Lavin, PhD, and Robert J. Genco, DDS
all of whom were investigators in
the pivotal clinical study to evaluate
GEM 21S. The award will be accepted
at the AAP’s opening ceremony
by Dr. Myron Nevins, senior investigator
and lead author of the paper.
“I am honored that our paper,
based on the scientific rigor and
positive results of the GEM 21S pivotal
clinical trial, was chosen to receive
such an esteemed award,” said
Dr. Lynch. “Recognition by a
preeminent organization such as the
American Academy of Periodontology
helps validate the scientific integrity
and potential clinical impact of GEM
21S, and its main component rhPDGF,
one of the key wound healing stimulators
in the body. Moreover, the observation
that GEM 21S stimulated bone regeneration
in the periodontal study suggests
the potential for positive results
in our ongoing orthopedic clinical
trials and will help pave the way
for future approvals for PDGF based
product candidates currently under
development.”
Additionally, clinical investigators
for the GEM 21S pivotal trial will
be presenting at six forums during
the AAP Annual Meeting highlighted
by two General Session presentations.
Dr. William Giannobile, who will present
at the General Session on Monday,
September 18, will provide long-term
12 and 24 month follow up data from
the GEM 21S pivotal trial. Dr. Michael
McGuire, who will present at the General
Session on Tuesday, September 19,
will discuss clinical case studies
demonstrating the use of PDGF for
gingival recession.
About BioMimetic Therapeutics
BioMimetic Therapeutics, Inc. is developing
and commercializing bio-active drug-device
combination products for the healing
of musculoskeletal injuries and disease,
including periodontal, orthopedic,
spine and sports injury applications.
BioMimetic received marketing approval
from the FDA for its first product,
GEM 21S®, as a grafting material
for bone and periodontal regeneration
following completion of human clinical
trials, which demonstrated the safety
and efficacy of its platform technology
in this indication. Additionally,
BioMimetic has clinical trials ongoing
for orthopedic bone healing indications.
The Company's product and product
candidates all combine recombinant
protein therapeutics with tissue specific
scaffolds to actively stimulate tissue
healing and regeneration.
Forward-looking Statements
This press release contains "forward-looking
statements" within the meaning
of the Private Securities Litigation
Reform Act of 1995. These forward-looking
statements are based on the current
intent and expectations of the management
of BioMimetic. These statements are
not guarantees of future performance
and involve risks and uncertainties
that are difficult to predict. There
are many important factors that could
cause actual results to differ materially
from those indicated in the forward-looking
statements. BioMimetic’s actual
results and the timing and outcome
of events may differ materially from
those expressed in or implied by the
forward-looking statements because
of risks associated with the marketing
of BioMimetic’s product and
product candidates, unproven preclinical
and clinical development activities,
regulatory oversight, and other risks
detailed in the company's filings
with the Securities and Exchange Commission,
including the section entitled "Risk
Factors" in its Prospectus dated
May 12, 2006, filed with the Securities
and Exchange Commission on May 12,
2006 and in the second quarter 2006
10Q dated August 9, 2006. Except as
required by law, BioMimetic undertakes
no responsibility for updating the
information contained in this press
release beyond the published date,
whether as a result of new information,
future events or otherwise, or for
changes made to this document by wire
services or Internet services.
For further information, visit www.biomimetics.com
or contact Kearstin Patterson, manager
corporate communications, at 615-236-4419.
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